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    PROGRESSION

    Pronunție (USA): Play  (GB): Play

    Traducere în limba română

    progression substantiv

    1. înaintare, avansare, păşire înainte, progresare;

    made of progression mod de înaintare, mod de locomoţie.

    2. (fig. rar) mers înainte, progres.

    3. (mat.) progresie;

    arithmetical progression progresie aritmetică;

    geometrical progression progresie geometrică.

    4. (rar lingv.) întărire (a unei vocale).

    5. (muz.) secvenţă (a părţilor).

     Exemple de propoziții și/sau fraze: 

    This gene is involved in transcriptional regulation, cell cycle progression and protein methylation.

    (MLL5 Gene, NCI Thesaurus)

    Treatment can slow its progression, but there is no cure.

    (Another Reason to Exercise: Protecting Your Sight, Editura Global Info)

    It currently is used to confirm diagnosis of pancreatic cancer or track disease progression rather than screen for the disease.

    (New Approach to Pancreatic Cancer Screening May Help Catch Disease Earlier, Editura Global Info)

    Researchers hope the treatment could stop the progression of MS. They say the trial is significant because they have shown the technique is safe and has had positive improvements in an autoimmune disease.

    (Multiple Sclerosis Treatment Developed in Australia Shows Promise, VOA)

    AG-024322 selectively inhibits cyclin-dependent kinases (particularly CDK1,2 and 4), enzymes that regulate cell cycle progression.

    (AG-024322, NCI Thesaurus)

    An inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival.

    (mTOR Kinase Inhibitor AZD8055, NCI Thesaurus)

    The oncogenic protein HER-2, a member of the human epidermal growth factor receptor (EGFR) family of tyrosine kinases, is overexpressed in a variety of cancers and is correlated with increased tumor growth, progression and a poor prognosis.

    (MVF-HER-2(597-626)/MVF-HER-2 (266-296) Peptide Vaccine, NCI Thesaurus)

    ATR, a serine/threonine protein kinase upregulated in a variety of cancer cell types, plays a key role in DNA repair, cell cycle progression and survival; it is activated by DNA damage caused during DNA replication-associated stress.

    (ATR Kinase Inhibitor AZD6738, NCI Thesaurus)

    Previous studies have suggested that both coffee and tea play an important role in modulating disease-risk in humans by suppressing tumor progression, decreasing inflammation and influencing estrogen metabolism, mechanisms that may be mediated by epigenetic changes.

    (Tea Consumption: Epigenetic Changes in Women, Editura Global Info)

    Semaphorin 4D, a large cell surface antigen found on the resting T-cell and overexpressed in a variety of tumor cell types, plays an important role in vascular growth, tumor progression, invasion and immune cell regulation.

    (Anti-SEMA4D Monoclonal Antibody VX15/2503, NCI Thesaurus)




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